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根据维基百科和百度百科上对Rush Popper的注释,Rush主要成分包括:亚硝酸丁酯(isoamyl nitrite)、亚硝酸异戊酯(isopentyl nitrite)、异丙基亚硝酸盐(2-propyl nitrite)和异亚硝酸盐(2-methylpropyl nitrite)等的综合。
虽然没有直接研究Rush的生殖毒性研究,但是有不少关于其中成分亚硝酸盐对精子和生殖的不良影响。列了一些如下。大家有代孕计划和想有孩子的话,还是要注意不要过度使用Rush。
1.Nitrite-induced testicular toxicity in rats: therapeutic potential of walnut oil.JBRA Assist Reprod
Not Found
2019
Adelakun SA, Ukwenya VO, Ogunlade BS, A J Aniah, G A Ibiayo.
2.Inhibition of NOS-NO System Prevents Autoimmune Orchitis Development in Rats: Relevance of NO Released by Testicular Macrophages in Germ Cell Apoptosis and Testosterone Secretion.PLoS One
2.74
2015
Jarazo Dietrich S, Fass MI, Jacobo PV, Sobarzo CM, Lustig L, Theas MS.
3.Testicular nitric oxide and thiobarbituric acid reactive substances levels in obstructive azoospermia: a possible role in pathophysiology of infertility.Mediators Inflamm
3.758
2006
Başar MM, Kisa U, Tuğlu D, Yilmaz E, Başar H, Cağlayan O, Batislam E.
4.Toxicology and carcinogenesis studies of sodium nitrite (CAS NO. 7632-00-0) in F344/N rats and B6C3F1 mice (drinking water studies).Natl Toxicol Program Tech Rep Ser
Not Found
2001
National Toxicology Program.
5.Increased nitric oxide production in the spermatic vein of patients with varicocele.Eur Urol
17.947
2000
Ozbek E, Turkoz Y, Gokdeniz R, Davarci M, Ozugurlu F.
6.Biphasic effect of nitric oxide on testosterone and cyclic GMP production by purified rat Leydig cells cultured in vitro.Int J Androl
Not Found
1999
Valenti S, Cuttica CM, Fazzuoli L, Giordano G, Giusti M.
7.Effects of nitric oxide on human spermatozoa: evidence that nitric oxide decreases sperm motility and induces sperm toxicity.Hum Reprod
5.733
1995
Rosselli M, Dubey RK, Imthurn B, Macas E, Keller PJ.
8.In vivo genotoxicity of nitrates and nitrites in germ cells of male mice. II. Unscheduled DNA synthesis and sperm abnormality after treatment of spermatids.Mutat Res
2.463
1988
Alavantić D, Sunjevarić I, Cerović G, Bozin D, Pecevski J.
9.In vivo genotoxicity of nitrates and nitrites in germ cells of male mice. I. Evidence for gonadal exposure and lack of heritable effects.Mutat Res
2.463
1988
Alavantić D, Sunjevarić I, Pecevski J, Bozin D, Cerović G.
10.Seminal plasma nitrite/nitrate and intratesticular Doppler flow in fertile and infertile subjects.Hum Reprod
5.733
2000
Battaglia C, Giulini S, Regnani G, Di Girolamo R, Paganelli S, Facchinetti F, Volpe A.
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